Updated 3 November 2026 · Root & Evidence editorial content · No independent clinical review claimed
Browse the human research behind our guides by ingredient, outcome, study type, or publication year. Open a record to see its findings, limitations, and original source.
9 selected publications · 6 ingredients. This is a curated collection of the research currently summarized on this site, not a complete clinical-trial registry or a live PubMed search. A review may include trials also listed separately; record counts are not counts of independent evidence. Publication filters use the cited publication year, not the date we added the record.
9 publications shown
No studies match these filters. Clear a filter or try another term. No match does not mean no human research exists.
Small improvement in self-reported insomnia symptoms.
Limitations: Questionnaires, brief follow-up, no comparison with other magnesium forms.
Root & Evidence: not yet rated. No certainty rating assigned to this record.
No consistent cardiometabolic benefit.
Limitations: Heterogeneity, bias, indirectness; sensitivity analysis weakened BP finding.
Root & Evidence: not yet rated. Authors’ GRADE: very low.
No conventionally significant benefit on either primary cognitive test.
Limitations: Task-specific outcomes; modest effects remain uncertain; not a dementia treatment trial.
Root & Evidence: not yet rated. No certainty rating assigned to this record.
Events: 12.0% versus 12.2%; HR 0.99.
Limitations: Stopped early for futility; distinct formulation and comparator.
Root & Evidence: not yet rated. No certainty rating assigned to this record.
Primary cardiovascular endpoint not significantly reduced.
Limitations: Primary prevention; secondary findings do not establish broad protection.
Root & Evidence: not yet rated. No certainty rating assigned to this record.
Primary events: 17.2% versus 22.0%; HR 0.75.
Limitations: Specific prescription EPA and high-risk population; not evidence for ordinary fish oil.
Root & Evidence: not yet rated. No certainty rating assigned to this record.
No significant between-group glucose or HbA1c difference.
Limitations: Small sample; too short for a strong HbA1c or long-term safety assessment.
Root & Evidence: not yet rated. No certainty rating assigned to this record.
Stress scores and cortisol favored the extract.
Limitations: Small, short study of a specific extract; cannot establish long-term safety or treat all anxiety disorders.
Root & Evidence: not yet rated. No certainty rating assigned to this record.
HbA1c fell within the berberine group from 9.5% to 7.5%.
Limitations: Small pilot; a similar observed response does not prove equivalence to metformin.
Root & Evidence: not yet rated. No certainty rating assigned to this record.